Secretin-Like Class B G Protein-Coupled Receptor (Gpcr) Mutation Data Set

Research datakeyboard_double_arrow_right Dataset 24 Aug 2016 Netherlands Publisher:ZenodoFunded by:NIH | GPCR Network, NIH | Technical Assistance to S..., NIH | JCIMPT-Complexes +4 projects

Authors: de Graaf, Chris;

doi: 10.5281/zenodo.60790

Secretin-Like Class B G Protein-Coupled Receptor (Gpcr) Mutation Data Set

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Abstract

Curated set of 2463 quantitative mutation data points covering 13 secretin-like class B G protein-coupled receptors. Annotated according to GPCRdb standards (http://gpcrdb.org/), complemented by GPCRdb Ballesteros-Weinstein numbers assigned using GPCRdb KNIME nodes (https://github.com/3D-e-Chem/knime-gpcrdb). The data set is build from data sets published in: - Siu et al. Nature 2013, 499: 444-449. doi:10.1038/nature12393 - Hollenstein, de Graaf et al. Tr Pharmacol Sci 2014, 35: 12-22. doi: 10.1016/j.tips.2013.11.001 - Yang, de Graaf et al. J Biol Chem 2016, 291: 12991-3004. doi: 10.1074/jbc.M116.721977

Country

Netherlands

Related Organizations

Vrije Universiteit Amsterdam
Netherlands

Keywords

calcitonin receptor-like receptor (CALRL), class B GPCR, glucagon like peptide 1 receptor (GLP-1R) , secretin receptor (SCTR), G protein-coupled receptor (GPCR), corticotropin releasing hormone receptor 2 (CRFR2), vasoactive intestinal peptide receptor 1 (VIPR1), glucagon like peptide 1 receptor (GLP-1R), parathyroid hormone 2 receptor (PTH2R), secretin-like receptors, corticotropin releasing hormone receptor 1 (CRFR1), vasoactive intestinal peptide receptor 2 (VIPR2), site directed mutagenesis, growth hormone-releasing factor receptor (GHRH), calcitonin receptor (CALCR), gastric inhibitory polypeptide receptor (GIPR), parathyroid hormone 1 receptor (PTH1R), glucagon receptor (GCGR)

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