Supplementary information, datasets and fluorescence images related to the article "The role of NSP6 in the biogenesis of the SARS-CoV-2 replication organelle". The PDF file entitled "Supplementary material" contains the uncropped original western blots and autoradiographs published in the article. The PDF files entitled "Extended Data Fig.2,6,7,9,10 all panels" and "Figure 1,4 all panels" contain the original full-size confocal immunofluorescence images from which specific ROIs are published in the article. The Excel files "Source Data Principal Figures" and "Source Data Extended Figures" contain all the original datasets used for calculation and graphical representation of data published in the article.