Medicinal Plant Chemistry Division, Central Institute of Medicinal and Aromatic Plants, Lucknow-226 015. India E-mail : root@cimap.sirnet.ernet.in Fax : 91-0522-342676 Manuscript received 21 December 2001, revised 4 April 2002. accepted 16 July 2002 A new acetophenone derivative 2-hydroxy-4,6-dimethoxyaeetophenone (1) along with a-santonin and 5-hydroxy-7.4'-dimethoxy-flavonc have been isolated from the aerial parts of Artemisiα mαritimα.