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Obtención de un candidato vacunal anti-garrapatas

Authors: Díaz Gonzalez, Omar; Rodríguez Mallon, Alina;

Obtención de un candidato vacunal anti-garrapatas

Abstract

Las garrapatas son artrópodos ectoparásitos que causan daños directos a los organismos que parasitan, su capacidad como vectores de muchos agentes patógenos diferentes que producen una alta morbilidad y mortalidad en los hospederos. El uso intensivo e indiscriminado de todo tipo de productos químicos ha conducido al desarrollo de cepas de garrapatas resistentes y multi-resistentes. La vacunación es el medio más deseable para combatir los agentes infecciosos. En este sentido del Centro de Imaginería Genética y Biotecnología trabaja en la obtención de una vacuna efectiva contra diferentes especies de garrapatas cuyo ingrediente farmacéutico activo es un conjugado entre un péptido de 20 aminoácidos de la proteína ribosomal acídica P0 de garrapatas (pP0) obtenido por síntesis química y la proteína Bm86 de R. microplus expresada en la levadura P. pastoris.

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selected citations
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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