Bacteriocins are ribosomally synthesised group of antimicrobial peptides synthesised by almost all groups of bacteria and demonstrates bactericidal or bacteriostatic activity, usually against members of closely related species and different strains of similar species. Bacteriocin has gained much attention worldwide over the last decade especially for their advantages in regards to physical stability and non-toxicity. Various bacteriocins have been reported to act as promising food preservatives or in the health industry as antimicrobial agents or bio-controlling agents and as so as for fight against antimicrobial drug resistance. They are also being exploited for their anticancer properties as a new tool in fighting cancer. Bacteriocins also plays a major role in food industry by safeguarding public health and food safety as they found their utility in chemical free preservation, enhancing shelf-life, and as well as inhibition of food-borne pathogenic microorganisms from farm till food-processing stages. Nanotechnology has proven to be effective drug delivery system and so as so as to avoid any existing limitation of bacteriocins. With the increasing bacterial resistance, the evolution of nanotechnology has proven to be an effective upgrade of traditional drug delivery systems. The incorporation of bacteriocins into nanoparticles and site-directed delivery to areas of infection may soon become an effective method of treatment.