The excel files includes the raw data for a paper presenting a regional, modular biorefinery concept for the production of the platform chemicals hydroxymethylfurfural (HMF), furfural and phenols from the lignocellulosic perennial miscanthus, which can be cultivated on marginal and degraded areas. The paper focuses on the question of the minimum selling price of HMF and the optimal plant size for this purpose, using the region of Baden-Württemberg, Germany, as an example. Based on small pilot plant results, a scalable process simulation was created via AspenPlus.