These databases are from the pilot clinical trial, Daily Caloric Restriction and Intermittent Fasting in Overweight and Obese Adults With Autosomal Dominant Polycystic Kidney Disease. This study determined the feasibility of delivering two behavioral weight loss interventions for 1 year in adults with autosomal dominant polycystic kidney disease (ADPKD) who were overweight or obese. The study also compared these two interventions in terms of safety, acceptability, and tolerability. Last, the trial will provided initial insight into a) biological changes and b) changes in kidney growth with each of the two weight loss interventions. The main data are provided as a SAS files (with data dictionaries), with adherence data as a SPSS file. The data are available to qualified individuals within the scientific community who apply for data use directly with the lead contact.