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Article . 2021
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Mammary-Type Myofibroblastoma of the Vulva: A Case Report and Review of the Literature

Authors: , Allagany; Vilos; Alzawawi; Haakman; Abu-Rafea; Vilos;

Mammary-Type Myofibroblastoma of the Vulva: A Case Report and Review of the Literature

Abstract

{"references": ["1. Wargotz ES, Weiss SW, Norris HJ. Myofibroblastoma of the breast. Sixteen cases of a distinctive benign mesenchymal tumor. Am J Surg Pathol. 1987; 11: 493-502.", "2. McMenamin ME, Fletcher CD. Mammary-type myofibroblastoma of soft tissue: a tumor closely related to spindle cell lipoma. Am J Surg Pathol. 2001; 25: 1022-1029", "3. Howitt BE, Fletcher CDM. Mammary-type Myofibroblastoma. Clinicopathologic Characterization in a Series of 143 Cases. Am J Surg Pathol. 2016; 40: 361-367.", "4. Kuyumcu G, Rubin BP, Winalski C. Imaging features of mammary-type myofibroblastoma of soft tissue: a case series with literature review. Skeletal Radiol. 2017; 46: 1283-1291.", "5. Diwadkar GB, Barber MD. Vulvar mammary-type myofibroblastoma: a case report. J Reprod Med. 2009; 54: 404-406.", "6. Wei Q, Zhu Y. Collision tumor composed of mammary-type myofibroblastoma and eccrine adenocarcinoma of the vulva. Pathol Int. 2011; 61: 138-142", "7. Magro G, Caltabiano R, Kacerovsk\u00e1 D, Vecchio GM, Kazakov D, Michal M. Vulvovaginal myofibroblastoma: expanding the morphological and immunohistochemical spectrum. A clinicopathologic study of 10 cases. Hum Pathol. 2012; 43: 243-253", "8. Zhang Y, Jorda M, Goldblum JR. Perianal mammary-type myofibroblastoma. Ann Diagn Pathol. 2010; 14: 358-360", "9. Abdul-Ghafar J, Ud Din N, Ahmad Z, Billings SD. Mammary-type myofibroblastoma of the right thigh: a case report and review of the literature. J Med Case Rep. 2015; 9: 126."]}

Abstract Background: Mammary-type myofibroblastomas (MTMF) have been reported to occur at extramammary sites throughout the body of men and women of all ages, including the vulvovaginal and perianal area where they can pose diagnostic and therapeutic challenge due to indistinguishable clinical features from malignant tumors. Case: A 35-year-old woman, para 1, gravida 3, presented with an asymptomatic 5 cm by 3 cm tumor located along the anterior half of the left labia majora near the clitoris. Following excisional biopsy under general anesthesia, histopathological and immunohistochemical studies showed features consistent with a diagnosis of MTMF. Conclusion: Vulvar MTMF is a rare benign soft tissue neoplasm but it warrants appropriate marginal excisional diagnosis since it is indistinguishable from benign and/or malignant lesions of the vulva

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Keywords

Myofibroblastoma, Mammary-type myofibroblastoma, Vulvar tumors

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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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