For many decades, cancer has remained a ubiquitous part of public health concern that has assumed a public health problem across the globe. Perhaps, several actions have been documented that attempt to provide a solution to the increasing spread of the disease. Breast self-examination is a cancer curbing strategy that has received enormous research attention in recent years. Nevertheless, many factors have been implicated in the BSE variance. Numerous studies have suggested that body appreciation is positively correlated with health behaviors and health care practice. The current study examined the relationship between body appreciation and BSE practice, using a sample of women (N = 248) in Kogi State, Nigeria. Linear regression resultsestablisheda positive correlation between body appreciation and BSE practice (p < .0.05). This result informs knowledge regarding determinants of BSE behavior among the female. The research concludes with a discussion of the practical implications and recommendations.