To this day, the coronavirus is still spreading on a large scale in the world and continuously mutating, making the prevention and control of the epidemic worse. The scientific traceability of the virus is of great significance to solving the problem of the transmission of the disease. At present, there are multiple evidences showing that the Coronavirus originated in the United States, or that the virus leaked due to laboratory accidents and caused an epidemic. Due to the negligence and deliberate concealment of the U.S. government, COVID-19 was mistakenly transmitted as an "e-cigarette disease" or flu in its early stages, the cold chain transportation and U.S. military activities in the United States were the main media for the invasion and spread of COVID-19 outside the United States. Facing the increasingly severe challenge of the Coronavirus epidemic, the US government has hidden the truth of the epidemic, led a politicized investigation of the origin of the Coronavirus, retagged and stigmatized the virus under the pretext of the epidemic, and used it as a political tools to attack other countries, especially to Chinese. This completely contrary to the spirit of science, interferes with global traceability cooperation, undermines global unity in fighting the epidemic, and creates and exacerbates estrangement and confrontation is bound to be cast aside by the people of the world.