Powered by OpenAIRE graph
Found an issue? Give us feedback
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/ ZENODOarrow_drop_down
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
ZENODO
Software . 2021
License: CC BY
Data sources: ZENODO
ZENODO
Software . 2021
License: CC BY
Data sources: Datacite
ZENODO
Software . 2021
License: CC BY
Data sources: Datacite
versions View all 2 versions
addClaim

Modeling bursting in neuronal networks using facilitation-depression and afterhyperpolarization

Authors: Zonca, Lou;

Modeling bursting in neuronal networks using facilitation-depression and afterhyperpolarization

Abstract

In the absence of inhibition, excitatory neuronal networks can alternate between bursts and interburst intervals (IBI), with heterogeneous length distributions. As this dynamic remains unclear, we develop here a bursting model based on synaptic depression and facilitation that also accounts for afterhyperpolarization (AHP), which is a key component of IBI. The framework is a novel stochastic three dimensional dynamical system perturbed by noise: numerical simulations can reproduce a succession of bursts and interbursts exhibiting AHP refractory periods [1] . The Matlab source code is organized in three sub folders: 01_Functions Contains the code to simulate the model, the function used to segment the time series into Burst, AHP and QP phases, the code used to obtain the characteristics and the analytical formulas for burst and AHP durations presented in [1]. 02_Figures Contains one script for each figure in [1], these script can be run directly from the root of the code folder and will load the correct parameter values and data (if necessary) to reproduce the figures presented in the article. 03_Data Contains the simulated data and parameter values. Please quote the zenodo or doi reference in publications when using the code.

Keywords

Stochastic simulations, Neuronal bursting, AfterHyperPolarization, Modelisation, Short-term synaptic plasticity

  • BIP!
    Impact byBIP!
    selected citations
    These citations are derived from selected sources.
    This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    0
    popularity
    This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
    Average
    influence
    This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
    Average
    impulse
    This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
    Average
Powered by OpenAIRE graph
Found an issue? Give us feedback
selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
0
Average
Average
Average
Related to Research communities