Analyses of human cancer driver genes uncovers evolutionarily conserved RNA structural elements involved in posttranscriptional control - associated datasets

These datasets include raw data output and associated files from ScanFold and CMbuilder analyses of human cancer driver gene mRNA. ScanFold was used to predict RNA regions of unusual thermodynamic stability, and CMbuilder was used to evaluate covariation of the predicted structures in those regions. Please view the file README_general_description_Zenodo_files.txt for brief descriptions of the content. These data are associated with the manuscript entitled Analyses of human cancer driver genes uncovers evolutionarily conserved RNA structural elements involved in posttranscriptional control. The manuscript has currently been submitted for review in PLOS ONE.

Thank you to NIH-NIGMS R01GM133810 for funding.

Related Organizations

Iowa State University
United States

Keywords

cancer driver, CMbuilder, mRNA, ScanFold, secondary RNA structure, RNA structure

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