This research aims at conducting a study of computerized application in medical diagnosis with reference to protein-protein interaction analysis of oxidative stress proteins in Alzheimer’s Disease (AD). It can help medical practitioners, representatives and scholars to better understand computer application in medical diagnosis specifically with regard to AD. This study can also offer them with potential topics for further investigation as well as give an idea about areas that are in need for improvement. This study has significance to the medical and healthcare community, as it will contribute to earlier research in the field of medical diagnosis, computer aided diagnosis, oxidative stress in Alzheimer’s disease, use of computer aided diagnosis for AD.