This is a database of the color-magnitude diagrams (CMDs) and fundamental parameters of star clusters in LISC catalogue. It corresponds to the study of Zhongmu Li et al. in 2021, which was submitted to ApJS. When one use these data, please cite to that work. Note that (V-I) color and V magnitude in the observed CMD data which are given in the database are transformed from the Gaia EDR3 magnitudes using some fitting correlations. The database contains three directories. These directories are explained as follows. (1)The first directory "all_clusters" gives the basic information and the observed CMD data of 3597 clusters in the work of Li et al.(2021). These clusters are all searched clusters by FOF and compared with previous catalogs. It has two subfolders and two files with '.dat' suffix. The first subfolder "new_candidates" contains observed CMD data of 868 clusters. These clusters are the different clusters in the previous catalogues, i.e., Liu & Pang(2019), Kharchenko et al.(2013), Cantat-Gaudin et al.(2018), Cantat-Gaudin et al.(2019), Bica et al.(2019), Castro-Ginard et al.(2019), Castro-Ginard et al.(2020), and Casado(2021) ,and the catalogue proposed in this work. Each file is named "obcmd_LISC****. dat".There are 10 columns in each file. The colums are for V, V-I, BP, BP-RP, ra, dec, parallax, rv, e_ra, e_dec respectively. The first and second columns are for V magnitude and V-I color which are transformed from the Gaia EDR3 magnitudes using some fitting correlations, and the other columns are the information of single star from Gaia EDR3. The second subfolder "matched_clusters" contains observed CMD data of 2729 clusters. These clusters are the same cluster in the previous catalogues, i.e., Liu & Pang(2019), Kharchenko et al.(2013), Cantat-Gaudin et al.(2018), Cantat-Gaudin et al.(2019), Bica et al.(2019), Castro-Ginard et al.(2019), Castro-Ginard et al.(2020), and Casado(2021), and the catalogue proposed in this work. The name and content of each file are the same as the file in the first subfolders. The first file "new_candidates" gives basic information of 868 candidates which corresponds to the candidates in the first subfolder. The second file "match_clusters.dat" gives basic information of 2729 clusters which corresponds to the clusters in the second subfolder of this directory. (2)The second directory "new_clusters" gives observed CMD data, best-fitted CMD data and best-fit parameters of 61 unknown clusters before. These clusters come from 868 star clusters that have not been matched by other catalogues. They were identified as potential new clusters in Li et al.(2021). These clusters are fitted via ASPS model and Powerful CMD code. Three parts of this directory are as follows. The first subfolder "obcmd" contains observed CMDs of 61 newly found clusters. The name and content of each file are the same as the file in the first subfolders of the first directory. The second subfolder "fitcmd" contains best-fitted CMDs of 61 new found clusters. These clusters are fitted by the ASPS model and Powerful CMD code. Each file is named "fitcmd_LISC****. dat". The first two lines give the best fitting parameters of the cluster. Note that "age0" is the age of the youngest star in the cluster if the stellar population type of cluster is composite stellar population(CSP). The first and second columns from the fourth row are for (V-I) color and V magnitude. The file "fit_parameter.dat" contains best-fit parameters of 61 new found clusters. There are 16 columns in this file. The colums are for id, ra, dec, plx,sig_plx, ����cos��,sig_����cos��, ����,sig_����, rsc, m-M, E(V-I), Z, t/t_range, f_bin and f_rot respectively. These parameters are the best-fit parameters by the ASPS model and Powerful CMD code. They correspond to the contents of a manuscript that was submitted to ApJS. (3)The third directory "known_clusters" gives observed CMD data, best-fitted CMD data and best-fit parameters of 594 known clusters. These clusters come from 2729 star clusters that have been matched by other catalogues. They have relatively clear CMDs structure and be fitted via ASPS model and Powerful CMD code. This directory have two subfolders. The first subfolder "good_fit" have the same structure with the second directory "new_clusters" but for 309 known clusters that have high quality CMDs and are fitted well. The second subfolder "other" have the same structure with the second directory "new_clusters" but for 285 known clusters that did not have high quality CMDs or are not well fitted. If you have any problems when using these data, send an email to Prof. Dr. Zhongmu LI, at email: zhongmuli@126.com.