ATR-FTIR spectra was acquired to detect and inspect physiological response to SARS-CoV-2 infection from saliva samples. Three experimental models were used to determine robustness of the technique. In vitro experiment tested supernatant derived from SARS-CoV-2 infected, UV-inactivated SARS-CoV-2 infected, or media control Vero cells. Supernatant collected at 24hr and 48hr post-infection. Data related to Figure 1. Mouse experiment tested oral lavage from mice exposed to SARS-CoV-2 or UV-inactivated SARS-CoV-2 virus. Lavage collected at 0, 2 and 4 days post-infection. Data related to Figure 2. Human experiment tested saliva collected at three different sites (NSW, TPCH, QIMR). Patients were tested for SARS-CoV-2 by gold standard PCR methods to determine infection status. PCR results and FTIR spectra included. Data related to Figure 3 and 4.

This data is uploaded to support a submitted manuscript. Publication DOI to follow once accepted.