A detailed ultrastructural examination of lung cryobiopsy samples from a COVID-19 patient case series – Data set 08

We investigated six cryobiopsy samples from six deceased patients (patients C03 to C08 from Barisione et al. 2020 doi.org/10.1007/s00428-020-02934-1) by using thin section electron microscopy (Cortese et al. 2022 doi.org/10.1007/s00428-022-03308-5). A detailed description of the methods and the data set is provided in the download container. Data set 08 contains stitched image montages of thin sections (selected areas) through the lung of patients C04 and C08 which were acquired by scanning electron microscopy (C04) or transmission electron microscopy (C08_A & B). The images show the pathological changes of the alveolar epithelium: Type-1-cells detachment from the basal membrane (C08_A & B) and type-2-cell hyperplasia (C04).

Related Organizations

University of Genoa
Italy
Robert Koch Institute
Germany

Keywords

alveolar damage, thin section, electron microscopy, SARS-CoV-2, COVID-19, cryobiopsy, patient, lung

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