This is the accepted manuscript version of the work published in its final form as Whitworth, H. S., Schiller, J., Markowitz, L. E., Jit, M., Brisson, M., Simpson, E., & Watson-Jones, D. (2021). Continued HPV vaccination in the face of unexpected challenges: A commentary on the rationale for an extended interval two-dose schedule. Vaccine, 39(6), 871–875. https://doi.org/10.1016/j.vaccine.2020.12.031. Deposited by shareyourpaper.org and openaccessbutton.org. We've taken reasonable steps to ensure this content doesn't violate copyright. However, if you think it does you can request a takedown by emailing help@openaccessbutton.org.