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pymCADRE: Tissue-specific model reconstruction

integration_instructionsResearch softwarekeyboard_double_arrow_right Software 13 Oct 2021Publisher:Zenodo
Authors: Leonidou, Nantia;
Code repository: https://github.com/draeger-lab/pymCADRE/tree/v1.2.0

doi: 10.5281/zenodo.5566815 , 10.5281/zenodo.7848063 , 10.5281/zenodo.5566128

pymCADRE: Tissue-specific model reconstruction

Abstract

pymCADRE is an advanced re-implementation of the metabolic Context-specificity Assessed by Deterministic Reaction Evaluation (mCADRE) algorithm in Python. It constructs tissue-specific metabolic models by leveraging gene expression data and literature-based evidence, along with network topology information.

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Keywords

python, genome-scale modeling, constraint-based modeling, tissue-specific reconstructions, flux balance analysis, sbml model

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selected citations
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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