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ZENODO
Dataset . 2021
License: CC BY
Data sources: Datacite
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ZENODO
Dataset . 2021
License: CC BY
Data sources: ZENODO
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figshare
Collection . 2022
License: CC BY
Data sources: Datacite
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ZENODO
Dataset . 2021
License: CC BY
Data sources: Datacite
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figshare
Collection . 2022
License: CC BY
Data sources: Datacite
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Claim

An intron SNP rs2069837 in IL-6 is associated with osteonecrosis of the femoral head development

Research datakeyboard_double_arrow_right Dataset , Collection 02 Sep 2021Publisher:Zenodo
Authors: Wang, Ruisong; Li, Rui; Liu, Ruiyu;

doi: 10.5281/zenodo.5372106 , 10.6084/m9.figshare.c.5780038.v1 , 10.5281/zenodo.5372105 , 10.6084/m9.figshare.c.5780038

An intron SNP rs2069837 in IL-6 is associated with osteonecrosis of the femoral head development

Abstract

Two variants (rs2069837, and rs13306435) in the IL-6 gene were identified and genotyped from 566 patients with ONFH and 566 healthy controls. The associations between IL-6 polymorphisms and ONFH susceptibility were assessed using odds ratio (OR) and 95% confidence interval (95% CI) via logistic regression. The results of the overall analysis revealed that IL-6 rs2069837 is correlated with decreased risk of ONFH among the Chinese Han population (p < 0.05). In stratified analysis, rs2069837 also reduced the susceptibility to ONFH in older people (> 51 years), males, nonsmokers, and nondrinkers (p < 0.05).

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Keywords

IL-6, ONFH, susceptibility, polymorphism

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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