The COVID-19 pandemic has put a huge strain on governments and medical professionals all across the world. To identify acceptable treatments, many clinical studies from the Indian system of Traditional Medicines [Ayurveda, Yoga and Naturopathy, Unani, Siddha, and Homoeopathy (AYUSH)] have been conducted. Objective of the study is determine the efficiency of the Traditional System of Indian Medicine (AYUSH system) in lowering the incidence, duration, and severity of COVID-19 through a living systematic review and meta-analysis. The review will be updated bi-monthly with two updates. It will provide practitioners, guideline developers, and authorities with up-to-date syntheses on interventions on a regular basis to help them make health-care decisions about AYUSH therapies for COVID-19 management. Study is supported by World Health Organization, South East Asia Regional Office, New Delhi, India. Here, we shared the PRISMA-P checklist of our project developed.