We are living in modern days and everyone is in hurry for everything even for their ailments. They required medicine that is fast acting although cause some harm to the body. That may be managed by time. Unani system of medicine (USM) is one of the oldest systems of medicine in the world providing treatment through its rich formulations based on single drugs. Unani medicinal plants are playing an important role in the drug discovery and development of new molecules. There are a number of unani drugs which are used from ancient time. For this review unani text as well as other ethnobotanical books were searched and presented the studies here. Action and Uses of Atees (Aconitum heterophyllum wall) mentioned in Unani literature along with phytochemistry and pharmacology. Total ten pharmacological activities were recognized in different experimental models. The antipyretic action of this drug has been proved in scientific study. The other actions of the drug mentioned in unani literature are to be validated on scientific parameters.