Submitted materials consist of study Dataset (Dataset_Migraine_Psycovid.xlsx) which includes socio-demographic data of 128 subjects (64 migraine patients; 64 healthy controls), clustering from HIT-6 and HIT-6 total score and perception of changes in motor and extra motor symptoms, with possible causes, for migraine patients; and the clinical and psychosocial variables used in the study (i.e., depression, stress, anxiety, loneliness, empathic skills, coping strategies) for all subjects. Study results showed higher general loneliness and lower social support in migraine patients compared to control subjects with emotional loneliness crucially differing in patients with high vs low headache impact. The headache impact, regardless of the migraine type, differentiated patients in the perception of changes in their clinical condition due to the restrictive measures, affecting particularly care paths and physical activity.