Supplementary Datasets for "A genome-wide optical pooled screen reveals regulators of antiviral responses" Supplementary Dataset 1. Mean per-gene extracted features for all channels of genome-wide screen Supplementary Dataset 2. Features from single cells in secondary antibody screen Supplementary Dataset 3. Features from single cells in secondary reporter screen Supplementary Dataset 4. IRF3 translocation scores from primary and secondary IRF3 antibody and IRF3 reporter screens (the latter upon both Sendai virus and VSV infection) and SeV intensity scores from secondary antibody screen. Supplementary Dataset 5. Peroxisome and Sendai virus feature scores from genome-wide screen