Model Of Striatum Medium Spiny Neurons

This is a subcellular signaling kinetic model of the striatal medium spiny neuron (msn) by Nair et al., (2015). It simulates the dopamine and acetylcholine dependent activation of cAMP/PKA in the dopamine type 1 receptor positive msn of the direct pathway. The full model description can be found in the BioModels database (https://www.ebi.ac.uk/biomodels-main/ Model id: MODEL1502200000).

{"references": ["doi: 10.1523/JNEUROSCI.0730-15.2015"]}

Related Organizations

Karolinska Institute
Sweden

Keywords

kinetic models, medium spiny neuron

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