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Data and code to reproduce all statistical analyses and figure in the manuscript "Response to Elexacaftor/Tezacaftor/Ivacaftor in intestinal organoids derived from patients with cystic fibrosis". The dataset is stored in the file `area_data.csv`, the columns are: `well` The ID of the well within the plate the measurement was taken `time` time from start of measurement `area` area of the organoids `patient` Anonymized ID of the patient `date` Date when the experiment was performed (date and patient ID identify the plate) `filename` The filename in raw data (not published) this plate was stored in. (uniquely identifies a plate) `mix` Identifies one od two variants of plate layouts used `replicate` ID of technical replicate (two technical replicates were done for each condition on the same plate) `type` The main condition - one of "TEZ/IVA", "ELX/TEZ/IVA", "FskOnly" (Control, only forskolin) `fsk_concentration` concentration of forskolin (μM) The file "organoids.Rmd" reproduces the analyses, other files are supporting to let the main analysis run. The analysis is written in R markdown.
cystic fibrosis, elexacaftor, tezacaftor, ivacaftor, organoids
cystic fibrosis, elexacaftor, tezacaftor, ivacaftor, organoids
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