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Dataset . 2021
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ZENODO
Dataset . 2021
License: CC BY
Data sources: Datacite
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ZENODO
Dataset . 2021
License: CC BY
Data sources: ZENODO
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ZENODO
Dataset . 2021
License: CC BY
Data sources: Datacite
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ZENODO
Dataset . 2021
License: CC BY
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Data and statistical analysis for: Response to Elexacaftor/Tezacaftor/Ivacaftor in intestinal organoids derived from patients with cystic fibrosis

Authors: Eva Furstova; Tereza Dousova; Jakub Beranek; Malgorzata Libik; Libor Fila; Martin Modrak; Ondrej Cinek; +2 Authors

Data and statistical analysis for: Response to Elexacaftor/Tezacaftor/Ivacaftor in intestinal organoids derived from patients with cystic fibrosis

Abstract

Data and code to reproduce all statistical analyses and figure in the manuscript "Response to Elexacaftor/Tezacaftor/Ivacaftor in intestinal organoids derived from patients with cystic fibrosis". The dataset is stored in the file `area_data.csv`, the columns are: `well` The ID of the well within the plate the measurement was taken `time` time from start of measurement `area` area of the organoids `patient` Anonymized ID of the patient `date` Date when the experiment was performed (date and patient ID identify the plate) `filename` The filename in raw data (not published) this plate was stored in. (uniquely identifies a plate) `mix` Identifies one od two variants of plate layouts used `replicate` ID of technical replicate (two technical replicates were done for each condition on the same plate) `type` The main condition - one of "TEZ/IVA", "ELX/TEZ/IVA", "FskOnly" (Control, only forskolin) `fsk_concentration` concentration of forskolin (μM) The file "organoids.Rmd" reproduces the analyses, other files are supporting to let the main analysis run. The analysis is written in R markdown.

Related Organizations
Keywords

cystic fibrosis, elexacaftor, tezacaftor, ivacaftor, organoids

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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