The present database contains observations for 22 parameters of abiotic, phyto and zooplankton data collected in the Northern Adriatic Sea region (Italy). It relies on a Comma Separated Values file and it is composed by 108687 records. Due to its long temporal coverage, it is classifiable as Long Term Ecological data. Due to the long temporal coverage, the great part of parameters changed collection and analysis method in time. These variations are reported in the database. A long-term database can be useful for multiple purposes. This database has been released under a research project focused on Open Science principles application to marine ecology, it is also deposited in B2Share repository (https://b2share.fz-juelich.de/records/f772ed02dcd1403a86fac5a6a19005ef) and metadata are available in DEIMS-SDR (Dynamic Ecological Information Management System - Site and dataset registry, https://deims.org/dataset/38d604ef-decb-4d67-8ac3-cc843d10d3ef). A datapaper, discussing methods, results and describing data has been published on Earth System Science Data (https://doi.org/10.5194/essd-12-215-2020).

Compared to the third version of the database, in this new version, we added taxa references, following WORMS standard) to the column names for Diato and Dino parameters, we added the corresponding URIs of sensors published on GET-IT in brackets (<>) near the sensor name, for each parameter. Alternate identifiers to part of the present database have been added.