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ZENODO
Dataset . 2021
License: CC BY
Data sources: Datacite
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
ZENODO
Dataset . 2021
License: CC BY
Data sources: Datacite
image/svg+xml art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos Open Access logo, converted into svg, designed by PLoS. This version with transparent background. http://commons.wikimedia.org/wiki/File:Open_Access_logo_PLoS_white.svg art designer at PLoS, modified by Wikipedia users Nina, Beao, JakobVoss, and AnonMoos http://www.plos.org/
ZENODO
Dataset . 2021
License: CC BY
Data sources: ZENODO
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Claim

Data related to article "miR-146a in Myasthenia Gravis Thymus Bridges Innate Immunity With Autoimmunity and Is Linked to Therapeutic Effects of Corticosteroids"

Research datakeyboard_double_arrow_right Dataset 13 Apr 2021Publisher:Zenodo
Authors: Bortone, Federica; Scandiffio, Letizia; Marcuzzo, Stefania; Bonanno, Silvia; Frangiamore, Rita; Antozzi ,Carlo; Motta, Teresio; +3 Authors

doi: 10.5281/zenodo.4683486 , 10.5281/zenodo.4683487

Data related to article "miR-146a in Myasthenia Gravis Thymus Bridges Innate Immunity With Autoimmunity and Is Linked to Therapeutic Effects of Corticosteroids"

Abstract

Raw data obtained by real-time PCR performed to assess the expression of miR-146a-5p and U6 endogenous control in: hyperplastic myasthenia gravis (MG) thymuses; normal thymuses; microdissected germinal centers (GCs) and surrounding thymic medulla from hyperplastic MG thymuses; peripheral blood mononuclear cells (PBMCs) and serum from MG patients and healthy controls; prednisone-treated PBMCs from MG patients and controls. Raw real-time PCR data obtained to assess mRNA levels of the miR-146a target genes, IRAK1, TRAF6, c-REL, ICOS, FAS and IRF8, and the endogenous 18S control, in hyperplastic MG and normal thymuses, microdissected MG GCs plus the surrounding thymic medulla. Confocal microscopy images of normal and hyperplastic MG thymuses after immunostainings performed to show: IRAK1 in combination with CD20 (B cell marker), cytokeratin (epithelial cell marker), CD11c (dendritic cell marker) and CD68 (macrophage marker); cREL in combination with CD20.

Study supported by Italian Ministry of Health - grants GR-2013-02358564; Ricerca Corrente_Cavalcante P, Linea 2

Related Organizations
Keywords

myasthenia gravis, thymus, MiR-146a, autoimmunity, innate immunity

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
views
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