The terminology of medicine within the systematic approach is studied as a well-ordered base with a specific set of components, structure, and functions inherent in a given terminological system, i.e. components making up the entire system, relations between the elements, the effect of the transformation of a particular element on other components and the whole system generally. In this regard, much attention in the systematic research of terminology is paid to the analysis of important system categories: components, contacts, structure. The choice of medical terminology as an object of study, in particular, the terminology of genetics can be explained by the fact that it represents an important communicatively lexical system that is constantly updated and intensively developed. Medical terminology is comparable to socio-political, sports and technical terminology, which is quite natural since medicine acts as a leading part in the process of comprehending the world, and the functional sphere of medicine is directly related to the life of a modern person. According to our observations, the derivation of the terminology space of genetics can be represented in the form of systemically organized, conceptually interconnected and interdependent blocks. The terminological system of genetics shows that it belongs to the class of adaptive self-organizing and self-adjusting systems. In this case, an adequate solution to the issue of polysemy is of great importance. This fact is related to the point that the terminology of different sciences can correlate and do not conflict with the properties of adjacent subsystems, which can contribute to the development of interbranch polysemy. The theoretical significance of the study helps to determine the place of the English medical terminology of genetics in the general vocabulary system. In practical terms, the results of the study can find application in creating a dictionary containing new words in fundamental lexicographic publications.