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Попытка применения нового индекса оценки активности ревматоидного артрита

Попытка применения нового индекса оценки активности ревматоидного артрита

Abstract

Почти вековая эволюция представлений о критериях активности ревматоидного (РА) артрита показала, что даже комплексные индексы для ее определения нуждаются в совершенстве. Поэтому сообщение в печати о новом индексе активности РА, включающем четыре лабораторных маркера оценки выраженности воспаления, вызвало повышенный интерес. Однако проведенное пилотное сравнительное исследование нового индекса и широко применяемого в клинической практике индекса DAS28 показало, что новый индекс не работает, вопреки заключению его авторов. В связи с этим необходимы дальнейшие исследования для валидации нового индекса активности РА поскольку в представленном виде он не позволяет оценить активность воспалительного процесса.

Keywords

ревматоидный артрит, DAS28, индексы активности воспаления, тромбоцитарные индексы

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This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
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