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TIGA: Target Illumination GWAS Analytics

Name: TIGA: Target Illumination GWAS Analytics
Keywords: illuminating the druggable genome, GWAS, drug discovery

descriptionPublicationkeyboard_double_arrow_right Conference object , Other literature type 10 Mar 2021Publisher:ZenodoFunded by:NIH | Illuminating the Druggabl..., NIH | Knowledge Management Cent...

Authors: Jeremy Yang; Dhouha Grissa; Stephen Mathias; Anna Waller; David Wild; Christophe Lambert; Lars Juhl Jensen; +1 Authors

doi: 10.5281/zenodo.4594200 , 10.5281/zenodo.4594201

TIGA: Target Illumination GWAS Analytics

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Abstract

Genome-wide association studies (GWAS) generate large volumes of associations between genomic variations and phenotypic traits. However, assessing strength, specificity and relevance of associations, and semantically valid aggregation of associations, for applications such as drug target prioritization, is challenging. This project addresses this challenge.

Related Organizations

University of New Mexico
United States
DePaul University
United States

Keywords

illuminating the druggable genome, GWAS, drug discovery

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NIH| Illuminating the Druggable Genome Knowledge Management Center (IDG KMC), NIH| Knowledge Management Center for Illuminating the Druggable Genome