Data for Developmental cell programs are co-opted in inflammatory skin disease - filtered, annotated anndata object

Dataset to accompany BioRxiv preprint "Poised cell circuits in human skin are activated in disease" (https://www.biorxiv.org/content/10.1101/2020.11.05.369363v1). Data in AnnData (h5ad) format. Preprocessed to exclude doublets and low quality cells (<200 genes and >20% mitochondrial content). Healthy.h5ad includes neighborhood graph and UMAP coordinates and annotation from the manuscript in figure 1B. Full dataset with annotation ("combined") in obs.

This has been updated - the previous version had multiple old annotations that are no longer in use,

Related Organizations

King's College London
United Kingdom
Newcastle University
United Kingdom

Keywords

skin disease, Full dataset, Science Policy, Developmental cell programs, Immunology, UMAP coordinates, BioRxiv preprint, Space Science, annotation, h 5ad format, quot, Genetics, anndata object Dataset, Developmental Biology, Cancer, Biological Sciences not elsewhere classified, neighborhood graph

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