Background: Sexually transmitted infections (STI) are a worldwide health problem and became a concern and burden on the healthcare systems. STIs are not so common in sexually abused children, however, when present, they can be crucial to making the diagnosis of sexual abuse and taking positives steps in protection of the children. The incidence of STIs in sexually abused children must be assessed as it may be useful in prevention of these infections and giving the appropriate attention to the problem of abuse of children may help in protection manners of these children. Aim: This study aims to review and discuss results of previous studied regarding prevalence, types and diagnostic implications of sexually transmitted infections in sexually abused children. Methodology: This is a systematic review was carried out, including PubMed, Google Scholar, and EBSCO that examining randomized controlled trials, observational, and experimental studies which study STI in sexually abused children. Results and Conclusion: The study included 6 studies and concluded that; sexually transmitted infections can be transmitted to children by sexual abuse. Any child with diagnosed STI must be assessed for sexual assault. Prevalence of STI, like C. trachomatis and N. Gonorrhea, which is low in children tested for potential sexual assault, has an effect on their favorable predictive value. Keywords: sexually transmitted infections, sexually abuse, children, STIs, sexual abuse, sexual assault