Based on own data, the basis positions concerning probiotic bifidobacteria as producers of adaptable and controlled network of functionally coupled antimycotics of the recognition type (lectin and lectin-like type) were described. Such antimycotics act as an organized ordered system of metabolomebiotics which are distinct from the classical antibiotics, acting with other (expanded) mechanisms resulting in increase of resistance of the organism protective network. Bifidobacterial antimycotics are represented by probiotc lectin and postbiotic systems of promised prophylactic and therapeutic significance in future.