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doi: 10.5281/zenodo.45311
deconstructSigs R package and README Takes sample information in the form of the fraction of mutations in each of 96 trinucleotide contexts and identifies the weighted combination of published signatures that, when summed, most closely reconstructs the mutational profile.
Oncology, R package, cancer genetics, Evolutionary biology, mutational signatures, Genetic variation, DNA
Oncology, R package, cancer genetics, Evolutionary biology, mutational signatures, Genetic variation, DNA
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