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Research . 2020
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Research . 2020
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CARACTERIZACIÓN FARMACOLÓGICA Y EVIDENCIA CIENTÍFICA DE USO DEL FAVIPIRAVIR PARA PACIENTES CON COVID-19 EN BOLIVIA

Authors: Martínez-Pérez, Scarley; Castillo-Vladislavic, Thania; Morales-Barroso, Nelly; Ramirez-Michel, Sandra; Arancibia, Gunnar;

CARACTERIZACIÓN FARMACOLÓGICA Y EVIDENCIA CIENTÍFICA DE USO DEL FAVIPIRAVIR PARA PACIENTES CON COVID-19 EN BOLIVIA

Abstract

El FAVIPIRAVIR es un derivado de pirazinacarboxamida oral y un análogo de guanina aprobado en algunos países para tratar la influenza, el ébola y el norovirus (McKee, Sternberg, Stange, Laufer, & Naujokat, 2020) puede ser encontrado en el mercado bajo las denominaciones de Avifavir, y Avigan Dado que la evidencia publicada para Favipiravir es limitada, se necesita más investigación para concluir su eficacia y seguridad para el tratamiento de pacientes con COVID-19. A la fecha se vienen ejecutando numerosos ensayos clínicos y es probable que se conozcan resultados en los próximos meses, estos hallazgos determinarán en última instancia si se debe usar Favipiravir más ampliamente en este entorno. Se recomienda considerar que, aunque el Favipiravir se desarrolló originalmente para tratar la influenza, el dominio catalítico RdRp (el objetivo principal de Favipiravir) es previsiblemente similar para otros virus de ARN, este dominio catalítico RdRp conservado contribuye a la cobertura de amplio espectro de Favipiravir. Acceda al artículo aquí

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Keywords

Favipiravir, Avifavir

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selected citations
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
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popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
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influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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