Abstract. The article presents the results of a study of the cardiovascular system of girls aged 7 and 8 years with vision impairment, and also presents the data of their comparative analysis with the hemodynamic parameters of healthy children. The features of the functional state of the cardiovascular system in children with visual impairment at relative rest, as well as at the beginning, middle and end of the school week at school, have been revealed. The study showed that the girls aged 7 and 8 years with visual impairment compared with healthy girls, at relative rest, have a lower level of functioning of hemodynamics, a negative shift in blood pressure and heart rate, and a tendency to a decrease in stroke volume and minute stroke volume. This may indicate the development of detraining of the cardiovascular system, the formation of a state of asthenia, due to forced hypodynamia and a decrease in the motor activity of visually impaired children. Regardless of age, all schoolgirls with visual impairment from the beginning to the middle of the school week have an increase in their blood pressure and heart rate, and at the end of the school week - a sharp decrease in cardiac output. That is, the observed functional rise of the circulatory system in the middle of the week is carried out due to a sharp increase in sympathetic influences, and a decrease in the contractile function of the heart indicates a low efficiency of the functioning of the cardiovascular system of visually impaired schoolgirls aged 7 and 8 years.