Background: Many systems have been involved in patients with diabetes mellitus in different ways. It is very crucial to know the electrocardiographic changes that can occur in patients with type 2 diabetes. Objective: To study ECG changes suggestive of myocardial ischemia in asymptomatic type II DM patients. To study correlation between HbA1c values and ECG changes in asymptomatic type II DM patients as compared to nondiabetic subjects (control group). Materials & method: Present cross sectional study carried out in tertiary care hospital from May 2015 to May 2017. 100 diabetic subjects (study group), 100 non diabetic subjects (control group) were selected for study randomly from various department of tertiary care hospital. In all study subject’s blood was tested for HbA1c & ECG changes were recorded. Results: There was significant difference between cases and controls for mean blood sugar level & mean HbA1c (p<0.01). ST segment changes, T wave inversion & Q-QS pattern were more among diabetic patient as compared to controls (p<0.01). Conclusion : ECG changes suggestive of myocardial ischemia or myocardial infarction in the form of ST segment changes, T wave changes and Q-QS pattern were significantly more in the study as compared to control group.