Buddhist befriending is holistic: it befriends human beings, even enemies, and nature too. In Buddhism one befriends others, in all circumstances and without discrimination, whether they are friends or enemies, offenders and prisoners, the poor and the needy. It also includes other religions and cultures as well as nature. We find several examples in the Buddhist texts, in history and in the contemporary world. This befriending is done with an altruistic spirit, with forbearance, loving friendship and compassion. As in all religions, however, there are exceptions in the texts, in history and in the modern world. Still, overall, Buddhism has been more peace-loving and non-violent than several other religions. Buddhist and Christian befriending do resemble each other, e.g., both are opposed to malice and both go to the extent of loving one’s enemy. Although there are similarities, there are also differences between Buddhism and Christianity with regard to the presuppositions, the cultivation, motivation and expression of befriending. While divergent world-views result in such differences, Buddhists, Christians and others need to hearken to the call of peace and altruistic love, to heal a broken world and build bridges of friendship and harmony with other human beings and with nature.