Aims: The aim of the study was to evaluate CRP and risk factors for ischemic stroke. Methods: This clinical study was conducted at the Department of Neurology, Services Hospital, Lahore for one-year duration from August 2019 to August 2020. The included stroke patients meeting inclusion and exclusion criteria. Results: Out of 30 patients with ischemic stroke, 28 (93.3%) patients had a positive value of C-reactive protein. 37% of stroke patients smoked cigarettes. Mean levels of total cholesterol, triglycerides, and LDL levels were higher, and mean HDL levels were lower in stroke patients compared to controls. 17% of stroke patients had diabetes, and 80% of stroke patients had high blood pressure. Conclusion: Elevated levels of C-reactive protein in the acute phase of ischemic stroke may be a prognostic marker. Key words: CRP, acute ischemic stroke