Objective: The aim of this study was to determine the frequency of microalbuminemia in type II diabetic patients and to compare lipid profile in type II diabetic patients with and without microalbuminuria Material and Methods: This study was carried out at allied hospital Faisalabad and the duration of this study was from January 2020 to December 2020. In this study, 300 diagnosed type-II diabetic cases between 35-70 years of age of either gender were included while those with macroalbuminuria Urinary albumin excretion > 300mg/d, increased serum creatinine 1.3 mg/dl for females and 1.5 mg/dl for male, having history of cardiovascular disease (History of typical cardiac chest pain, evidence of ischemic heart disease changes on ECG), urinary tract infection and pregnant women were not included. Results: In our study, mean age was 53.18+9.32 years, 43.90%(n=151) were male and 56.10% n=193 were females, frequency of microalbuminuria in type II diabetes mellitus was recorded in 32.56% n=112. Conclusion: the frequency of microalbuminuria in type II diabetic patients is higher while the frequency of hypertriglyceridemia’s, increased LDL-C and decreased HDL-C in Type II diabetic patients is significantly higher in patients with microalbuminuria when compared them without microalbuminuria. Keywords: Micro Albuminemia, Lipid Profile, Diabetes Mellitus, Endothelial Dysfunction.