Diabetes Insipidus is caused by a lack of antidiuretic hormone or ADH or a lack of response to antidiuretic hormone. The antidiuretic hormone acts on the collecting ducts in the kidneys and allows them to reabsorb water from the urine; having diabetes Insipidus prevents the kidneys from being able to concentrate the urine, and this leads to polyuria or excessive amounts of urine and polydipsia or excessive thirst because the blood is so concentrated it can be classified as cranial and nephrogenic diabetes insipidus depending on whether the problem is in the kidneys or the brain and an essential diagnosis of diabetes insipidus is primary polydipsia, and this is where the patient has a normally functioning ADH system. Still, they are drinking an excessive quantity of water, leading to excessive urine production. They don’t have diabetes insipidus, but they present with polyuria and often polydipsia. It is fundamental to carry out a knowledgeable evaluation based on describing features, intercede quickly with the appropriate treatment, and re-examine the patient’s condition. The proper treatment relies on the cause of the individual patient. Consequently, the doctor should decide whether the deformity is in the cerebrum (brain) or the kidney.