These are the assemblies and annotation products of a transcriptome assembled from regenerating and non-regenerating tissues of the California blackworm Lumbriculus variegatus. The assembly and annotation strategies are described in the article Transcriptome analysis during early regeneration of Lumbriculus variegatus, published in Gene Reports (https://doi.org/10.1016/j.genrep.2021.101050). blastp.outfmt6: homology results from BLASTp (v2.10.0) of the predicted proteins blastx.outfmt6: homology results from BLASTx (v2.10.0) of the assembled transcripts LV_transcriptome.fasta: assembled transcriptome after duplicated sequences were filtered out with CD-HIT-EST (v4.7) LV_transcriptome.fasta.transdecoder.cds: coding sequences identified with TransDecoder (v5.5.0) LV_transcriptome.fasta.transdecoder.gff3: positional annotation of the ORFs identified with TransDecoder (v5.5.0) LV_transcriptome.fasta.transdecoder.pep: predicted proteins identified with TransDecoder (v5.5.0) LV_transcriptome_non_filtered.fasta: transcriptome assembled with Trinity (Galaxy v0.0.1) signalp.out: signal peptide predictions from signalP (v4.1) tmhmm.out: transmembrane domains predictions from tmHMM (v2.0) TrinotatePFAM.out: protein domains predictions from HMMER (v3.3)