COVID-19 is basically a RNA virus and the nucleic acid is about 30 kb long, positive in sense, single stranded and polyadenylated. The main objective of the study is to analyse the influence of empowered work environments on the psychological experiences of nursing assistants during COVID-19. This descriptive cross sectional study was conducted in Lady Willingdon Hospital Lahore during June 2020 to November 2020. The data was collected from hospital nursing staff for the analysis of work environment during COVID-19. The data was collected through a semi structured questionnaire and interview. The data was collected from 100 nursing staff of the hospital. The average age was 43 ± 5.90 years and most of the staff was female. All provided care to COVID-19 patients regardless of the unit that they were assigned to. The psychological experience of impact did not emerge under the information and support constructs. It is concluded that management and empowerment of NAs are critical to hospital performance and success as empowered NAs have been shown to improve their job satisfaction, performance, morale, and retention.