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Effects of trabectedin in the zebrafish Danio rerio: from cells to larvae

Authors: Damasceno, Évila Pinheiro; Charlie-Silva, Ives; Glaucia Maria Machado-Santelli; Anali M. B. Garnique; Machado-Neto, João Agostinho; Teixeira, Simone Aparecida; Jimenez, Paula C.; +5 Authors

Effects of trabectedin in the zebrafish Danio rerio: from cells to larvae

Abstract

These archives contain the original data set for the research article "Effects of trabectedin in the zebrafish Danio rerio: from cells to larvae" FACS_ZFL_cells_Trabectedin.rar Contains the original data regarding cells morphology evaluated by flow cytometry (Becton Dickinson FACScan). Original data set_ This archive contains the original data tables for the research article "Effects of trabectedin in the zebrafish Danio rerio: from cells to larvae" Original data set_Spreadsheet Trypan Blue test_in vitro Cells viability on ZFL exposed to trabectedin measured by Trypan blue dye exclusion method Original data set_Spreadsheet MTT test_in vitro Cytotoxicity of trabectedin and doxorubicin (positive control) against ZFL cells as analyzed by the MTT assay Original data set_Spreadsheet Survival_in vivo Percentage of zebrafish embryos under trabectedin exposure Original data set_Spreadsheet Abnormalities_in vivo Percentage of abnormalities (somite alteration, pericardial edema, tail malformations, lack of equilibrium) of zebrafish embryos under trabectedin exposure Original data set_Spreadsheet Swimming behavior_in vivo Total distance covered and mean velocity by zebrafish larvae (120 hpf) after exposure to trabectedin

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Keywords

anticancer agents, locomotor behavior, developmental toxicity, cytotoxicity, survival

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selected citations
These citations are derived from selected sources.
This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
views
OpenAIRE UsageCountsViews provided by UsageCounts
downloads
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0
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28
3