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This dataset contains digitized patient level time to event data for overall survival of patients with locally advanced and metastatic (stage IIIB/IV) Non-small cell lung cancer (NSCLC). The data can be used to recreate the original Kaplan-Meier survival curves that were published in randomized controlled trials, in order to perform secondary analysis on the survival data. In order to recreate a survival curve, you need two csv.files per trial arm that are in this database: (1) starting with 'surv_', containing the individual patient level time to event data, and (2) starting with 'natrisk_', containing the corresponding numbers at risk table. For the methodology and r-code that can be used for this purpose we refer to article that is linked to this dataset.
The "Technology Assessment of Next Generation Sequencing in Personalized Oncology" (TANGO) project is funded by the ZonMw Personalised Medicine Programme under Dossier number: 846001002 in collaboration with KWF and Zilveren Kruis. The project period is 31 December 2016 – 31 May 2021.
Time-To-Event, Personalized Oncology, Whole Genome Sequencing, Overal Survival, Kaplan-Meier, Next Generation Sequencing, Targeted Therapy, NSCLC, Non-Small Cell Lung Cancer, Technology Assessment, NGS, Randomized Controlled Trial, Systematic Review, Immunotherapy, Metastatic Cancer, RCT, WGS
Time-To-Event, Personalized Oncology, Whole Genome Sequencing, Overal Survival, Kaplan-Meier, Next Generation Sequencing, Targeted Therapy, NSCLC, Non-Small Cell Lung Cancer, Technology Assessment, NGS, Randomized Controlled Trial, Systematic Review, Immunotherapy, Metastatic Cancer, RCT, WGS
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