Identification and validation of 174 COVID‑19 vaccine candidate epitopes reveals low performance of common epitope prediction tools

Datasets used in "Identification and validation of 174 COVID‑19 vaccine candidate epitopes reveals low performance of common epitope prediction tools" sars-cov-2_predicted.csv SARS-CoV-2 peptides predicted to be binders to 11 HLA alleles by the NetMHC suite tools, these selected peptides have been measured in a stability assay revealing SARS-CoV-2 epitopes (assay results can be found at: https://www.immunitrack.com/free-coronavirus-report-for-download/). tools_predictions_binders.xlsx File containing all predictions for tools tested in the benchmark (note that not all tools use same measure). List of binders (epitopes) with IEDB links and T cell studies overlap.

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Keywords

HLA, epitope, SARS-CoV-2, vaccine, COVID-19, MHC, vaccine candidates

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