Convolutional Neural Net (CNN) models for ENCODE-Roadmap DNase-seq peaks and Transcription Factor ChIP-seq peaks - Basset architecture

Deep learning models trained on epigenomic landscapes from ENCODE and Roadmap Epigenomics. The models are Basset convolutional neural networks (Kelley, et al 2016). The dataset used to train these models can be found at https://doi.org/10.5281/zenodo.4059038. The file `nn.encode-roadmap.models.basset.clf.tar.gz` contains 10 cross-validated models in Tensorflow framework files as well as details on the architecture, cross-validation scheme, and training of these models. The file `nn.encode-roadmap.models.basset.clf.np_weights.tar.gz` contains the 10 cross-validated models' weights extracted to numpy array files (.npz).

Keywords

chromatin accessibility, transcription factors, deep learning, gene regulation, neural networks

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