Introduction Induced lactation is a process by which breast milk is produced in a mammal (woman), without given birth and/or been pregnant. Eorts to produce milk by women who had never been pregnant and giving birth are not easy. It is far more arduous a task than initiating postpartum lactation, but it is possible and worth the eort, according to the many who have attempted it. Objective This qualitative study was to explore, identify and understand the key challenges for women during the process of induced lactation in Malaysia. Methodology This qualitative study utilized in-depth interview induced lactation’s women in five states based on five regions [Northern region (Penang), Southern region (Johor), East Coast region (Kelantan), Malaysia Borneo (Sabah)]. The interviews were consented, audio-recorded then transcribed verbatim, followed by identification of emerging themes. Results and Discussion Data saturation was achieved after interviewing a total of 23 induced lactation’s women. Data synthesized using thematic analysis also revealed that six mains key challenges such as women’s health condition, work commitment, overexertion, not eligible to take leave, inability to follow the treatment plan, and diculty in getting the adopted baby to initiate breastfeeding during induced lactation process. Conclusion The findings of this research will be able to help other women and their spouses/partners in comprehending the challenges, obstacles and support that are needed along induced lactation process. In addition, more eorts and programs should be undertaken by the government and other stakeholders to help these mothers able to breastfeed their adoptive child and makes them feel more accomplish as women and mothers