Objective. Among the choices of lens implantation like- iris-claw lenses, anterior chamber lenses and scleral or iris fixated lenses in aphakic eyes without capsular support, the iris-claw retropupillary lens implantation is gaining the popularity at present. Our aim of this study was to report the safety and efficacy of retropupillary iris-claw lens implantation in our institution. Methods. In this study 29 eyes of 29 patients with aphakia without capsular support were included prospectively from 2013-2018. All the patients were evaluated properly and subsequently retropupillary iris-claw lens implantation was done. Results. The mean age of patients was 62.3 years with SD of 11.2 years. Highest number of patients were in the age group of 60-70 years (43%). The mean follow-up of patients was 2.7 years ranging from two months to five years. Out of 29 eyes, 22 (75%) eyes had visual acuity of 6/9, three (10%) eyes had 6/12 and two eyes had 6/6 vision. The most common postoperative complication was subconjunctival hemorrhage, seen in 12 (41%) cases. Two eyes developed secondary glaucoma in postoperative period due to pupillary block. Retinal detachment was observed in one eye. We have not seen any case of bullous keratopathy, infection or cystoid macular edema till last follow-up. Conclusion. In aphakic eyes without capsular support, retropupillary iris-claw lens implantation is easy to perform and gives us the good refractive outcome with all the physiological and optical advantages of posterior intraocular lens location at low risk of complication.