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Fibrinogen-mimicking, multiarm nanovesicles for human thrombus-specific delivery of tissue plasminogen activator and targeted thrombolytic therapy

descriptionPublicationkeyboard_double_arrow_right Article , Other literature type 04 Jun 2021 United Kingdom English Publisher:American Association for the Advancement of Science (AAAS)Journal:Science Advances, volume 7 (eissn: 2375-2548, Copyright policy )Funded by:UKRI | Enhancing the MRC Nationa..., UKRI | Future Vaccine Manufactur...
Authors: Yu Huang; Boram Gu; Isabelle I. Salles-Crawley; Kirk A. Taylor; Li Yu; Jie Ren; Xuhan Liu; +6 Authors

doi: 10.1126/sciadv.abf9033 , 10.5281/zenodo.3982667 , 10.5281/zenodo.3982666

pmid: 34078604

pmc: PMC8172176

handle: 10044/1/89297

Fibrinogen-mimicking, multiarm nanovesicles for human thrombus-specific delivery of tissue plasminogen activator and targeted thrombolytic therapy

Abstract

Bioinspired nanovesicles enable activated platelet–targeted delivery of tissue plasminogen activator for effective thrombolysis.

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Keywords

Fibrinolytic Agents, Tissue Plasminogen Activator, 610, Fibrinogen, Humans, Thrombolytic Therapy, Thrombosis, Research Articles

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selected citations
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This is an alternative to the "Influence" indicator, which also reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Citations provided by BIP!
popularity
This indicator reflects the "current" impact/attention (the "hype") of an article in the research community at large, based on the underlying citation network.
BIP!Popularity provided by BIP!
influence
This indicator reflects the overall/total impact of an article in the research community at large, based on the underlying citation network (diachronically).
BIP!Influence provided by BIP!
impulse
This indicator reflects the initial momentum of an article directly after its publication, based on the underlying citation network.
BIP!Impulse provided by BIP!
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